Etiology of Isolated Third, Fourth, and Sixth Cranial Nerve Palsies with a Cancer History

Purpose: To investigate the causes of isolated ocular motor nerve palsy in patients with a history cancer.Methods: The charts 30 cancer diagnosed acquired third, fourth, and sixth cranial palsies from March 2013 to December 2021 were retrospectively reviewed. Sex, age onset, underlying disease analyzed.Results: Sixth (n = 18, 60.0%) was most common. Brain metastasis 13, 43.3%) common etiology, followed by microvascular 11, 36.7%), radiation-induced neuropathy 2, 6.7%), undetermined 4, 13.3%). Among 13 due brain metastasis, only one (7.7%) had been complete remission for more than 1 year. Of remaining 17 other causes, seven (41.2%) previously year.Conclusions: In cancer, cause, it likely if primary not magnetic resonance imaging should be performed as soon possible confirm differential diagnosis including various is also important.